Premig is used for migraines and the prevention of nausea and vomiting. It treats the symptoms associated with migraine. These symptoms include nausea, headache and vomiting. It is a non-steroidal drug and doesn’t cause inflammation. Premig consists of two active ingredients, which are lysine acetylsalicylate and Metoclopramide. Lysine acetylsalicylate is commonly known as Aspirin, and acts as a painkiller. Aspirin belongs to the group of medicines which are both non-steroidal and non-inflammatory. The other ingredient, Metoclopramide, is useful for treating the sickness and vomiting accompanying the migraine. Both ingredients are used together because metoclopramide enhances the absorption of aspirin, which can otherwise be slowed due to gastric stasis.
It is recommended that Premig should be taken as soon as possible when a migraine attack begins, for maximum effectiveness. This is because the absorption of Acetylsalicylate lysine can be slowed during migraine attacks because of their severity. The effective dosage of Premig is 3 sachets a day. However, you can take varying doses in accordance with what has been prescribed by your doctor. It is highly recommended that the doses should not be exceeded for increasing effectiveness, and the prescription should be followed exactly. Before obtaining a prescription, you should tell the doctor about your exact medical conditions and whether you are allergic to any ingredients. If you are taking insulin, Phenobarbital, Amobarbital, herbal medicines, vitamins or any other painkilling medication, you should inform the doctor.
Premig cures nausea and prevents vomiting as well as relieving the pain. The Metoclopramide in Premig takes acts by blocking the dopamine receptors, which are found in the chemoreceptor trigger zone of the brain. Metoclopramide causes the muscles in the stomach to contract, hence causing the food in the stomach to move to the intestines. This helps in preventing vomiting and also cures the heartburn felt due to the fullness of the stomach. This also makes the absorption of the drug quicker. Premig also relieves inflammation, heartburn and stomach pains. This is due to the drug blocking the production of Prostaglandins, which are responsible for causing inflammation, swelling and pain.
While taking Premig you should be careful as it causes drowsiness, and you should not drive unless you are sure about the affect that the drug has on you. The most common side effects of the drug are drowsiness, depression, skin rashes or other allergic reactions, blood disorders, fatigue, restlessness and dizziness. In some cases, it can also cause an inability to sleep. There can also be some other reactions to the drug in which case the doctor should be consulted immediately. These reactions include shaking limbs, mood changes and depression, and involuntary movements of different parts of the body.
This article is for informational purposes only. For further instructions on Premig consult with your doctor.
3 sachets/day (1620 + 10mg/sachet)
Possible side effects:
- difficulty in sleeping (insomnia)
- blood disorders
- allergic reactions such as skin rash